Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6937
Title: Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis
Authors: Ghosh, A. K.
Nyalapatla, R. P.
Kovela, S.
Rao, K. V.
Brindisi, Margherita 
Osswald, H. L.
Amano, M.
Aoki, M.
Agniswamy, J.
Wang, Y. -F.
Weber, I. T.
Mitsuya, H.
Keywords: Catalytic Domain; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Ligands; Models, Molecular; Molecular Structure; Protein Conformation; Stereoisomerism; Structure-Activity Relationship; Crystallography, X-Ray; Drug Design
Issue Date: 2018
Project: None 
Journal: JOURNAL OF MEDICINAL CHEMISTRY
Description: 
180367
URI: http://hdl.handle.net/20.500.12779/6937
ISSN: 0022-2623
DOI: 10.1021/acs.jmedchem.8b00298
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