Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6936
Title: Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand
Authors: Ghosh, A. K.
Ghosh, K.
Brindisi, Margherita 
Lendy, E. K.
Yen, Y. -C.
Kumaragurubaran, N.
Huang, X.
Tang, J.
Mesecar, A. D.
Keywords: Alzheimer's disease; BACE-1; Isoxazoline; Memapsin 2; β-secretase; Alanine; Amides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Bridged Bicyclo Compounds; Carboxylic Acids; Catalytic Domain; Crystallography, X-Ray; Cysteine; Humans; Isoxazoles; Molecular Structure; Protease Inhibitors
Issue Date: 2018
Project: None 
Journal: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Description: 
180371
URI: http://hdl.handle.net/20.500.12779/6936
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2018.06.045
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