Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6884
Title: KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease
Authors: Antognelli, Cinzia
Trapani, Eliana
Delle Monache, Simona
Perrelli, Andrea
Daga, Martina
Pizzimenti, Stefania
Barrera, Giuseppina
Cassoni, Paola
Angelucci, Adriano
Trabalzini, Lorenza 
Talesa, Vincenzo Nicola
Goitre, Luca
Retta, Saverio Francesco
Keywords: Adaptive redox homeostasis; Antioxidant defense; Argpyrimidine-modified heat-shock proteins; c-Jun; CCM1/KRIT1; Cerebral Cavernous Malformations; Cerebrovascular disease; Glyoxalase 1 (Glo1); Heme oxygenase-1 (HO-1); Nuclear factor erythroid 2-related factor 2 (Nrf2); Oxidative DNA damage and apoptosis; Oxidative stress; Redox signaling; Biochemistry; Physiology (medical)
Issue Date: 2018
Project: None 
Journal: FREE RADICAL BIOLOGY & MEDICINE
Description: 
136008
URI: http://hdl.handle.net/20.500.12779/6884
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2017.11.014
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