Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6789
Title: Design, Synthesis, Biological Evaluation, and X‐ray Studies of HIV‐1 Protease Inhibitors with Modified P2′ Ligands of Darunavir
Authors: Ghosh, Arun K.
Fyvie, W. Sean
Brindisi, Margherita 
Steffey, Melinda
Agniswamy, Johnson
Wang, Yuan-Fang
Aoki, Manabu
Amano, Masayuki
Weber, Irene T.
Mitsuya, Hiroaki
Keywords: drug resistance; HIV-1 protease inhibitors; P2â ² ligands; pharmacokinetics; structure-based design; Crystallography, X-Ray; Darunavir; HIV Protease; HIV Protease Inhibitors; Ligands; Models, Molecular; Molecular Conformation; Structure-Activity Relationship; Drug Design; Molecular Medicine; Pharmacology, Toxicology and Pharmaceutics (all); Organic Chemistry
Issue Date: 2017
Project: None 
Journal: CHEMMEDCHEM
Description: 
126209
URI: http://hdl.handle.net/20.500.12779/6789
ISSN: 1860-7179
DOI: 10.1002/cmdc.201700614
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