Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6745
Title: Toward a generalized computational workflow for exploiting transient pockets as new targets for small molecule stabilizers: Application to the homogentisate 1,2-dioxygenase mutants at the base of rare disease Alkaptonuria
Authors: Bernini, Andrea 
Galderisi, Silvia 
Spiga, Ottavia 
Bernardini, Giulia 
Niccolai, Neri 
Manetti, Fabrizio 
Santucci, Annalisa 
Keywords: Homogentisate 1,2-dioxygenase; Pharmacological chaperones; Transient pockets; Structural Biology; Biochemistry; Organic Chemistry; Computational Mathematics
Issue Date: 2017
Project: None 
Journal: COMPUTATIONAL BIOLOGY AND CHEMISTRY
Description: 
115068
URI: http://hdl.handle.net/20.500.12779/6745
ISSN: 1476-9271
DOI: 10.1016/j.compbiolchem.2017.08.008
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