Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6715
Title: Phenylpyrrole-based HDAC inhibitors: synthesis, molecular modeling and biological studies
Authors: Brindisi, Margherita 
Cavella, Caterina
Brogi, Simone
Nebbioso, Angela
Senger, Johanna
Maramai, Samuele 
Ciotta, Alfonso
Iside, Concetta
Butini, Stefania 
Lamponi, Stefania 
Novellino, Ettore
Altucci, Lucia
Jung, Manfred
Campiani, Giuseppe 
Gemma, Sandra 
Keywords: HDAC; antitumor agents; bioinformatics; drug design; enzyme inhibitors; epigenetics
Issue Date: 2016
Project: None 
Journal: FUTURE MEDICINAL CHEMISTRY
Abstract: 
Histone deacetylases (HDACs) regulate the expression and activity of numerous proteins involved in the initiation and progression of cancer. Currently, three hydroxamate-containing HDAC pan-inhibitors have been approved as antitumor agents.
Description: 
98316
URI: http://hdl.handle.net/20.500.12779/6715
ISSN: 1756-8919
DOI: 10.4155/fmc-2016-0068
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