Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6692
Title: 4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling
Authors: Trist, Iuni M. L.
Nannetti, Giulio
Tintori, Cristina
Fallacara, ANNA LUCIA
Deodato, Davide
Mercorelli, Beatrice
Palù, Giorgio
Wijtmans, Maikel
Gospodova, Tzveta
Edink, Ewald
Verheij, Mark
De Esch, Iwan
Viteva, Lilia
Loregian, Arianna
Botta, Maurizio 
Keywords: Animals; Antiviral Agents; Crystallography, X-Ray; DNA-Directed RNA Polymerases; Dogs; Drug Design; HEK293 Cells; Humans; Influenza A virus; Influenza, Human; Madin Darby Canine Kidney Cells; Models, Molecular; Molecular Docking Simulation; Pyridines; Structure-Activity Relationship; Viral Plaque Assay; Viral Proteins; Virus Replication; Medicine (all); Molecular Medicine; Drug Discovery3003 Pharmaceutical Science
Issue Date: 2016
Project: None 
Journal: JOURNAL OF MEDICINAL CHEMISTRY
Description: 
89130
URI: http://hdl.handle.net/20.500.12779/6692
ISSN: 0022-2623
DOI: 10.1021/acs.jmedchem.5b01935
Appears in Collections:Publications

Show full item record

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.