Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6679
Title: Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors
Authors: Savi, Lida
Brindisi, Margherita 
Alfano, Gloria
Butini, Stefania 
La Pietra, Valeria
Novellino, Ettore
Marinelli, Luciana
Lossani, Andrea
Focher, Federico
Cavella, Caterina
Campiani, Giuseppe 
Gemma, Sandra 
Keywords: Adenosine kinase; Ala-scan mutagenesis; Allosteric binding site; Allosteric inhibitors; Drug discovery; Non-nucleoside human AK inhibitors; Small molecule; Biochemistry; Molecular Medicine
Issue Date: 2016
Project: None 
Journal: CHEMICAL BIOLOGY & DRUG DESIGN
Description: 
111771
URI: http://hdl.handle.net/20.500.12779/6679
ISSN: 1747-0277
DOI: 10.1111/cbdd.12630
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