Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6653
Title: Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility
Authors: Mugnaini, Claudia 
Brizzi, Antonella 
Ligresti, Alessia
AllarĂ , Marco
Lamponi, Stefania 
Vacondio, Federica
Silva, Claudia
Mor, Marco
Di Marzo, Vincenzo
Corelli, Federico 
Keywords: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Ligands; Mice; Molecular Structure; NIH 3T3 Cells; Quinolones; Receptor, Cannabinoid, CB2; Solubility; Structure-Activity Relationship; Water; Molecular Medicine; Drug Discovery3003 Pharmaceutical Science; Medicine (all)
Issue Date: 2016
Project: None 
Journal: JOURNAL OF MEDICINAL CHEMISTRY
Description: 
204916
URI: http://hdl.handle.net/20.500.12779/6653
ISSN: 0022-2623
DOI: 10.1021/acs.jmedchem.5b01559
Appears in Collections:Publications

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