Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6562
Title: 4-Methylbenzylidene camphor microspheres: reconstituted epidermis (Skinethic) permeation and distribution
Authors: D. Monti, P. Chetoni, S. Burgalassi, S. Tampucci, M. Centini and C. Anselmi
Keywords: 4-methylbenzylidene camphor; microspheres; permeation; reconstituted epidermis; skin distribution
Issue Date: 2015
Project: None 
Journal: INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
Abstract: 
The UV filter 3(4-methylbenzylidene) camphor (4-MBC) is a common ingredient in sunscreen cosmetic products. However, different ‘in vitro’ and ‘in vivo’ studies suggest that 4-MBC can cause endocrine disrupting effects. Therefore, there is a need for new systems able to minimize the skin penetration of this UV filter. The aim of this study was to evaluate cutaneous permeation and distribution, through and into EPISKIN reconstituted epidermis (RE) from an O/W emulsion containing 4-MBC free or encapsulated in polymeric substantive microspheres.
Description: 
68609
URI: http://hdl.handle.net/20.500.12779/6562
ISSN: 1468-2494
DOI: 10.1111/ics.12199
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