Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6482
Title: Hotspots in an Obligate Homodimeric Anticancer Target. Structural and Functional Effects of Interfacial Mutations in Human Thymidylate Synthase
Authors: Salo Ahen, Outi M. H
Tochowicz, Anna
Pozzi, Cecilia 
Cardinale, Daniela
Ferrari, Stefania
Boum, Yap
Mangani, Stefano 
Stroud, Robert M
Saxena, Puneet
Myllykallio, Hannu
Costi, Maria Paola
Ponterini, Glauco
Wade, Rebecca C.
Keywords: tymidylate synthase, hot spot, FRET, x-ray crystallography, inhibition, dissociation, dimer interface
Issue Date: 2015
Project: None 
Journal: JOURNAL OF MEDICINAL CHEMISTRY
Description: 
67849
URI: http://hdl.handle.net/20.500.12779/6482
ISSN: 1520-4804
DOI: 10.1021/acs.jmedchem.5b00137
Appears in Collections:Publications

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