Please use this identifier to cite or link to this item:
|Title:||Synthesis of α,β-unsaturated aldehydes based on a one-pot phase-switch dehydrogenative cross-coupling of primary alcohols||Authors:||Mura, Manuel G
De Luca, Lidia
Williams, Jonathan M. J
|Keywords:||Alcohols; Aldehydes; Catalysis; Molecular Structure; Ruthenium; Stereoisomerism||Issue Date:||2014||Project:||None||Journal:||ORGANIC LETTERS||Abstract:||
An efficient one-pot ruthenium-catalyzed hydrogen-transfer strategy for a direct access to α,β-unsaturated aldehydes has been developed. The employment of enolates prepared in situ from alcohols avoided handling unstable aldehydes and provided a very appealing route to different cinnamaldehydes substituted in position 2. A silica-grafted amine was used as phase-switch tag leading to a selective one-pot process in favor of cross-dehydrogenative coupling products.
|Appears in Collections:||Publications|
Show full item record
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.