Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6266
Title: States of water, surface and rheological characterisation of a new biohydrogel as articular cartilage substitute
Authors: Leone, Gemma 
Bidini, Alessandra
Lamponi, Stefania 
Magnani, Agnese 
Keywords: POLY(VINYL ALCOHOL) HYDROGEL; HYDROXYAPATITE; SPECTROSCOPY; REPLACEMENT; DERIVATIVES; COMPOSITE
Issue Date: 2013
Project: None 
Journal: POLYMERS FOR ADVANCED TECHNOLOGIES
Abstract: 
PVA based hydrogel was synthesised using, as crosslinking agent, trisodium trimetaphosphate (STMP) and its morphology was modified inducing a microporous structure to obtain potential substitutes for cartilage tissue. The hydrogel was characterised by Infrared Spectroscopy combined with Time of flight mass spectrometry (ToF-SIMS) that confirmed the successful occurrence of crosslinking reaction, the hyphotised crosslinking arm and its homogeneous distribution. The mechanical spectra of the fully hydrated samples confirmed covalently crosslinked systems with a rheological behaviour similar to that of tibial cartilage. Further analysis in terms of water content measurements, thermal stability and cytotoxicity confirmed the applicability of such a hydrogel as cartilage substitute.
Description: 
59226
URI: http://hdl.handle.net/20.500.12779/6266
ISSN: 1042-7147
DOI: 10.1002/pat.3150
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