Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/6120
Title: Selective ozone concentrations may reduce the ischemic damage after a stroke
Authors: Frosini, Maria
Contartese, Antonella
Zanardi, Iacopo
Travagli, Valter 
Bocci, Velio
Issue Date: 2012
Project: None 
Journal: FREE RADICAL RESEARCH
Abstract: 
Stroke is one of the most debilitating diseases, and it is unfortunate that only a small percentage of patients can be treated with thrombolytic agents. Consequently, there is an urgent need of finding an alternative procedure for reoxygenating the so-called penumbra at the earliest time as possible for reducing morbidity and disability. A preliminary, preclinical study has been carried out by using rat hippocampal and cortical brain slices subjected to oxygen-glucose deprivation. Oxygen-ozone gaseous mixture appeared to be effective in reverting damage of brain tissues, supporting the evaluation of this approach in well-designed clinical trials in stroke patients.
Description: 
41754
URI: http://hdl.handle.net/20.500.12779/6120
ISSN: 1071-5762
DOI: 10.3109/10715762.2012.659247
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