Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5773
Title: Iron-catalyzed cross-coupling between 1-Bromoalkynes and grignard-derived organocuprate reagents
Authors: Castagnolo, Daniele
Botta, Maurizio 
Issue Date: 2010
Project: None 
Journal: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Abstract: 
An efficient iron-catalyzed cross-coupling reaction between alkynyl bromides and Grignard-derived organocuprates has been developed. A series of alkynylarenes were successfully synthesised by starting from different 1-bromoalkynes and Grignard reagents. The methodology was successfully used for the two-step stereoselective synthesis of combretastatins and represents a valid alternative to the classical syntheses of alkynylarenes.
Description: 
22442
URI: http://hdl.handle.net/20.500.12779/5773
ISSN: 1434-193X
DOI: 10.1002/ejoc.201000393
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