Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5677
Title: Polarographic Determination of Voriconazole in Pharmaceutical Formulations.
Authors: Corbini, Gianfranco 
Zanfini, Assunta
LA ROSA, Caterina
D'Arpino, A
Meucci, R
Dreassi, Elena 
Keywords: Voriconazole; Vfend®; DPP; Tablets; Injectables; Quantitative analysis
Issue Date: 2009
Project: None 
Journal: CURRENT ANALYTICAL CHEMISTRY
Abstract: 
This paper describes a method for voriconazole assay in pharmaceuticals by using differential pulse polarography (DPP). The voriconazole standard was obtained from pharmaceutical formulations and its purity determined by LC/UV, LC/ESI/MS and DSC analyses. In the DPP analysis a well defined peak (-1.01 V, vs. Ag/AgCl), useful for an accurate and precise assay, was obtained using a 0.01 M KH2PO4 water solution (pH 4.5) as supporting electrolyte. The analytical procedure was successfully applied to the voriconazole determination in tablets and injectables.
Description: 
35962
URI: http://hdl.handle.net/20.500.12779/5677
ISSN: 1573-4110
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