Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5664
DC FieldValueLanguage
dc.contributor.authorROWINSKA ZYREK, Men_us
dc.contributor.authorValensin, Danielaen_us
dc.contributor.authorSzyrwiel, Len_us
dc.contributor.authorGrzonka, Zen_us
dc.contributor.authorKozlowski, H.en_us
dc.date.accessioned2021-03-30T15:54:14Z-
dc.date.available2021-03-30T15:54:14Z-
dc.date.issued2009-
dc.identifier.issn1477-9226en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12779/5664-
dc.description26954en_US
dc.description.abstractThe medicinal application of bismuth compounds is focused in two fields: antimicrobial and anticancer. Bi(III) complexes have been used in medicine as an effective treatment of microbial infections, such as peptic ulcers, diarrhoea, gastritis and syphilis. 212Bi and 213Bi are strong a-particle emitters, which, bound to specific ligands, could be promising targeted radio-therapeutic agents for the treatment of cancer. In this work, the coordination of bismuth to three peptides with the Cys-Xaa-Cys motif was studied by potentiometric, spectroscopic, mass spectrometric and NMR methods. We have shown, that sulfur atoms from cysteines are critical donors for the coordination of Bi(III). Our investigation provides insight towards an understanding of the chemistry of bismuth-containing complexes and may lead to the further application of this metal in medicine.en_US
dc.language.isoenen_US
dc.relationNoneen_US
dc.relation.ispartofDALTON TRANSACTIONSen_US
dc.titleSpecific interactions of Bi(III) with Cys-Xaa-Cys unit of a peptide sequenceen_US
dc.typeArticleen_US
dc.identifier.doi10.1039/b913430aen_US
dc.identifier.scopus2-s2.0-70350218973en_US
dc.identifier.isiWOS:000270973800009en_US
dc.relation.volume42en_US
dc.description.firstpage9131en_US
dc.description.lastpage9140en_US
dc.description.thirdmissionNot applicableen_US
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeArticle-
item.fulltextNo Fulltext-
crisitem.author.orcid0000-0003-4187-3919-
Appears in Collections:Publications
Show simple item record

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.