Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5589
Title: Domino alkylation-cyclization reaction of propargyl bromides with thioureas/thiopyrimidinones: a new facile synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones
Authors: Castagnolo, Daniele
Pagano, Mafalda
Bernardini, Martina
Botta, Maurizio 
Issue Date: 2009
Project: None 
Journal: SYNLETT
Abstract: 
A new synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones was developed as a domino alkylation-cyclization of propargyl bromides with thioureas and thiopyrimidinones, resp. Domino reactions were performed under microwave irradn. leading to the desired compds. in a few minutes and high yields.
Description: 
44568
URI: http://hdl.handle.net/20.500.12779/5589
ISSN: 0936-5214
DOI: 10.1055/s-0029-1217700
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