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|Title:||Domino alkylation-cyclization reaction of propargyl bromides with thioureas/thiopyrimidinones: a new facile synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones||Authors:||Castagnolo, Daniele
A new synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones was developed as a domino alkylation-cyclization of propargyl bromides with thioureas and thiopyrimidinones, resp. Domino reactions were performed under microwave irradn. leading to the desired compds. in a few minutes and high yields.
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