Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5586
Title: Four-Component Reactions toward Fused Heterocyclic Rings
Authors: Airiau, E
Girard, N
Mann, A
Salvadori, J
Taddei, Maurizio 
Issue Date: 2009
Project: None 
Journal: ORGANIC LETTERS
Abstract: 
A multicomponent reaction between H2, CO, an unsaturated carboxylic acid derivative, and binucleophiles has been discovered. This process represents a combination of diversity-oriented synthesis and multicomponent reactions including amidation and hydroformylation, followed by nucleophilic addition to an N-acyliminium ion allowing the generation of six new bonds. Using π-nucleophiles, the sequence turns into a multicomponent Pictet-Spengler reaction.
Description: 
21951
URI: http://hdl.handle.net/20.500.12779/5586
ISSN: 1523-7060
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