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|Title:||Discovery of new therapeutic targets by the informational spectrum method||Authors:||Nevena, Veljkovic
Veljković, Veljko J.
|Issue Date:||2008||Project:||None||Journal:||CURRENT PROTEIN & PEPTIDE SCIENCE||Abstract:||
The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational spectrum method (ISM), a virtual spectroscopy method for structure/function analysis of proteins, in identification of functional protein domains representing candidate therapeutic targets for drugs against human immunodeficiency virus (HIV)-1, anthrax, highly pathogenic influenza virus H5N1 and cardiovascular diseases.
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