Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5493
Title: Practical synthesis of novel purine analogues as Hsp90 inhibitors.
Authors: Semeraro, T
Mugnaini, Claudia 
Manetti, Fabrizio 
Pasquini, S
Corelli, Federico 
Issue Date: 2008
Project: None 
Journal: TETRAHEDRON
Abstract: 
The development of a straightforward synthesis of 4-amino-6-benzyl-6H-pyrrolo[3,4-d]pyrimidine and 7-amino-2-benzyl-2H-pyrazolo[4,3-d]pyrimidine derivatives allowed for the preparation of a small family of potential Hsp90 inhibitors. Some of the newly synthesized compounds showed Hsp90 inhibitory activity in preliminary biological assays.
Description: 
38286
URI: http://hdl.handle.net/20.500.12779/5493
ISSN: 0040-4020
DOI: 10.1016/j.tet.2008.09.030
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