Please use this identifier to cite or link to this item:
|Title:||Napthoxazepine Inhibitors of HIV-1 Integrase: Synthesis and Biological Evaluation||Authors:||Antonio, Garofalo
HIV-1 integrase is an important target for the identification of novel antiretroviral compounds potentially active against HIV-1 replication. Previously, we discovered several novel thiazolothiazepine derivatives as IN inhibitors with antiviral activity on cell-based assays. Due to their low cytotoxicity, low molecular weight, drug-like properties, and structural novelty, we embarked on a study to optimize the original lead compounds.
|Appears in Collections:||Publications|
Show full item record
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.