Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5459
DC FieldValueLanguage
dc.contributor.authorD., Mercurien_us
dc.contributor.authorLeone, Gemmaen_us
dc.contributor.authorBarbucci, Rolandoen_us
dc.contributor.authorR., Favaloroen_us
dc.contributor.authorA., Facchinien_us
dc.contributor.authorF., Signorien_us
dc.contributor.authorS., Broncoen_us
dc.contributor.authorF., Ciardellien_us
dc.date.accessioned2021-03-30T15:51:50Z-
dc.date.available2021-03-30T15:51:50Z-
dc.date.issued2008-
dc.identifier.issn1022-1360en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12779/5459-
dc.description36210en_US
dc.description.abstractDegeneration of intervertebral discs is the most common cause of back pain. The first phase of this degenerative process involves the nucleus pulposus. A rapid recovery of this structure can prevent further degradation of the annulus fibrosus. Guar Gum is an hydrophilic polysaccharide extracted from the seed endosperm of a plant. Through a cross linking procedure a Guar hydrogel was synthesized. The Guar hydrogel could be injected by a syringe and it is a good candidate as a nucleus pulposus substitute. For the preparation of the artificial fibrosus annulus, commercially available polymer materials are tuned to achieve suitable mechanical properties. To achieve this peculiar behaviour, the main strategy investigated is the dispersion of hollow polymer micro spheres in a thermoplastic polymer matrix. Processing conditions and particle content are finely tuned to get the target mechanical behaviour.en_US
dc.language.isoenen_US
dc.relationNoneen_US
dc.relation.ispartofMACROMOLECULAR SYMPOSIAen_US
dc.subjectannulus fibrosus; guar gum; hydrogel; intervertebral disc degeneration; nucleus polposusen_US
dc.titleAn Artificial Disc: Chemical and Biomechanical Analysisen_US
dc.typeArticleen_US
dc.identifier.doi10.1002/masy.200850614en_US
dc.identifier.scopus2-s2.0-54949149077en_US
dc.identifier.isiWOS:000257561100015en_US
dc.relation.volume266(1)en_US
dc.description.firstpage74en_US
dc.description.lastpage80en_US
dc.description.thirdmissionNot applicableen_US
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeArticle-
item.fulltextNo Fulltext-
crisitem.author.orcid0000-0002-0820-6068-
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