Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5449
Title: Oxidative damage mediated by herbicides on yeast cells
Authors: Braconi, Daniela 
Possenti, Silvia
Laschi, Marcella
Geminiani, M
Lusini, P
Bernardini, Giulia 
Santucci, Annalisa 
Issue Date: 2008
Project: None 
Journal: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Abstract: 
Agricultural herbicides are among the most commonly used pesticides worldwide, posing serious concerns for both humans, exposed to these chemicals through many routes, and the environment. To clarify the effects of three herbicides as commercial formulations (namely, Pointer, Silglif, and Proper Energy), parameters related to oxidative issues were investigated on an autochthonous wine yeast strain. It was demonstrated that herbicides were able to affect the enzymatic activities of catalase and superoxide dismutase, as well as to induce carbonylation and thiol oxidation as post-translational modifications of proteins. Saccharomyces cerevisiae is an optimal model system to study responses to xenobiotics and oxidative stress. Thus, the results obtained could further the understanding of mechanisms underlying the toxicity of herbicides.
Description: 
37121
URI: http://hdl.handle.net/20.500.12779/5449
ISSN: 0021-8561
DOI: 10.1021/jf800074p
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