Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5448
Title: Towards novel S-DABOC inhibitors: Synthesis, biological investigation, and molecular modeling studies.
Authors: Botta, Maurizio 
Angeli, Lucilla
Franchi, Luigi
Contemori, Lorenzo
Maga, G
Samuele, A
Zanoli, S
ARMAND UGON, M
Gonzalez, E
Llano, A
Esté, Ja
M., Botta
Keywords: HIV-1; Reverse Transcriptase; Mutant; NNRTIs; S-DABOCs; Molecular modeling
Issue Date: 2008
Project: None 
Journal: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Abstract: 
A small family of S-DABO cytosine analogs (S-DABOCs) has been synthesized and biologically evaluated as HIV-1 inhibitor both on wild type (wt) and drug-resistant mutants leading to the identification of an interesting compound (5d). Molecular modeling studies have been finally performed in order to rationalize the results.
Description: 
22402
URI: http://hdl.handle.net/20.500.12779/5448
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2008.09.070
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