Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5346
Title: Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies.
Authors: Mugnaini, Claudia 
Rajamaki, S
Tintori, Cristina
Corelli, Federico 
Massa, Silvio
Witvrouw, M
Debyser, Z
Veljkovic, V
Botta, Maurizio 
Issue Date: 2007
Project: None 
Journal: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Abstract: 
The identification of a novel hit compound as integrase binding inhibitor has been accomplished by means of virtual screening techniques. A small family of structurally related molecules has been synthesized and biologically evaluated with one of the compounds showing an IC(50)=12 microM.
Description: 
37175
URI: http://hdl.handle.net/20.500.12779/5346
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2007.08.005
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