Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5332
Title: Postgenomics of Neisseria meningitidis for vaccines development
Authors: Bernardini, Giulia 
Braconi, Daniela 
Martelli, Paola
Santucci, Annalisa 
Issue Date: 2007
Project: None 
Journal: EXPERT REVIEW OF PROTEOMICS
Abstract: 
Neisseria meningitidis infection still remains a major life-threatening bacterial disease worldwide. The availability of bacterial genomic sequences generated a paradigm shift in microbiological and vaccines sciences, and post-genomics (comparative genomics, functional genomics, proteomics and a combination/evolution of these techniques) played important roles in elucidating bacterial biological complexity and pathogenic traits, at the same time accelerating the development of therapeutic drugs and vaccines. This article summarizes the most recent technological and scientific advances in meningococcal biology and pathogenesis aimed at the development and characterization of vaccines against the pathogenic meningococci.
Description: 
37784
URI: http://hdl.handle.net/20.500.12779/5332
ISSN: 1478-9450
DOI: 10.1586/14789450.4.5.667
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