Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5323
Title: Synthesis and biological evaluation of 4-alkylamino-6-(2-hydroxyethyl)-2-methylthiopyrimidines as a new ribella virus inhibitors
Authors: Mugnaini, Claudia 
Petricci, Elena 
Botta, Maurizio 
Corelli, Federico 
Mastromarino, P.
Giorgi, Gianluca 
Issue Date: 2007
Project: None 
Journal: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Abstract: 
In the search for new chemotherapeutic agents useful against Rubella virus (RV) infections, a solution-phase parallel approach for the synthesis of a small library of 4-alkylamino-6-(2-hydroxyethyl)-2-methylthiopyrimidines has been set up, based on previous results from our research group. Biological evaluation of the newly synthesized compounds pointed out their interesting properties as anti-RV agents with IC(50) values in the micromolar range.
Description: 
35048
URI: http://hdl.handle.net/20.500.12779/5323
ISSN: 0223-5234
DOI: 10.1016/j.ejmech.2006.09.002
Appears in Collections:Publications

Show full item record

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.