Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5307
DC FieldValueLanguage
dc.contributor.authorM., Radien_us
dc.contributor.authorPetricci, Elenaen_us
dc.contributor.authorCorelli, Federicoen_us
dc.contributor.authorBotta, Maurizioen_us
dc.date.accessioned2021-03-30T15:50:36Z-
dc.date.available2021-03-30T15:50:36Z-
dc.date.issued2007-
dc.identifier.issn0385-5414en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12779/5307-
dc.description36543en_US
dc.description.abstractCoupling reaction of 2-substituted-6-methyl-4(3H)-pyrimidinones (la,b) with I-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (ABR) afforded the corresponding N1-2,6-disubstituted nucleosides (2a,b) without any trace of the N3-isomer. The 2-methylthio-6-methyl derivative (2b) has then proved to be a key intermediate for the synthesis of N1-6-methyluridine (4) and the corresponding N1-2-amino-6-metyhl derivative (5), suggesting the possibility to obtain different 2,6-disubstituted derivatives by means of methylthio nucleophilic substitution. A successful solid phase application was also shown.en_US
dc.language.isoenen_US
dc.relationNoneen_US
dc.relation.ispartofHETEROCYCLESen_US
dc.titleStereoselective Synthesis of N1-6-Methyluridine and Related 2-Substituted Analoguesen_US
dc.typeArticleen_US
dc.identifier.doi10.3987/COM-06-S(K)3en_US
dc.identifier.scopus2-s2.0-34547844088en_US
dc.identifier.isiWOS:000246698900006en_US
dc.relation.volume72en_US
dc.description.firstpage79en_US
dc.description.lastpage83en_US
dc.description.thirdmissionNot applicableen_US
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeArticle-
item.fulltextNo Fulltext-
crisitem.author.orcid0000-0002-9685-6342-
crisitem.author.orcid0000-0002-5750-4504-
crisitem.author.orcid0000-0003-0456-6995-
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