Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5043
Title: Design, Synthesis, and Binding Studies of New Potent Ligands of Cannabinoids Receptors
Authors: Brizzi, Antonella 
Brizzi, Vittorio
M. G., Cascio
T., Bisogno
Sirianni, Rossella
V., Dimarzo
Issue Date: 2005
Project: None 
Journal: JOURNAL OF MEDICINAL CHEMISTRY
Abstract: 
Despite their different chemical structures D9-tetrahydrocannabinol (THC) and anandamide (AEA) have common pharmacological properties. This study was aimed at finding new cannabinoid receptor ligands that overcome the instability of AEA and its analogues. To this end we planned the synthesis of a series of compounds which retained both a rigid structure, like that of plant cannabinoids, and a flexible portion similar to that of anandamide.
Description: 
26341
URI: http://hdl.handle.net/20.500.12779/5043
ISSN: 0022-2623
DOI: 10.1021/jm0501533
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