Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/5029
Title: Synthesis of reactive cytidine derivatives as building blocks for cross-linking oligonucleotides
Authors: Radi, Marco
Mugnaini, Claudia 
Petricci, Elena 
Corelli, Federico 
Botta, Maurizio 
Issue Date: 2005
Project: None 
Journal: TETRAHEDRON LETTERS
Abstract: 
6-Vinvlcytidine derivative (1) possessing good Michael acceptor properties has been synthesized through C-6 formylation and subsequent Wittig reaction. In view of introducing the reactive nucleoside into the oligonucleotide sequence, protection of the vinyl group as ethylthio derivative was proved to be effective for the masking and subsequent regeneration or the reactive vinyl moiety.
Description: 
35309
URI: http://hdl.handle.net/20.500.12779/5029
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2005.04.083
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