Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/4953
DC FieldValueLanguage
dc.contributor.authorN., D'Amelioen_us
dc.contributor.authorGaggelli, Elenaen_us
dc.contributor.authorGaggelli, Nicolaen_us
dc.contributor.authorF., Mancinien_us
dc.contributor.authorE., Moltenien_us
dc.contributor.authorValensin, Danielaen_us
dc.contributor.authorValensin, Giannien_us
dc.date.accessioned2021-03-30T15:45:50Z-
dc.date.available2021-03-30T15:45:50Z-
dc.date.issued2004-
dc.identifier.issn0712-4813en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12779/4953-
dc.description35225en_US
dc.description.abstractThis work provides evidence that paramagnetic lanthanide ions constitute ideal probes suitable for investigations of metal effects upon peptide-receptor interactions with the use of NMR methods. Cerium(Ill) is herein used for assessing metal effects upon the interaction between angiotensin II and a fragment from the AT(1A) receptor. Angiotensin II forms a complex with cerium(Ill) in water while the fCT(300-320) receptor fragment is poorly affected by cerium(III). However, the addition of the fragment displaces cerium(III) from the complex, thus directly demonstrating the higher affinity of angiotensin II for the receptor and probing the peptide residues involved in receptor binding.en_US
dc.language.isoenen_US
dc.relationNoneen_US
dc.relation.ispartofSPECTROSCOPYen_US
dc.titleProbing the role of metal ions on reversible peptide-protein interactions by NMRen_US
dc.typeArticleen_US
dc.identifier.doi10.1155/2004/583454en_US
dc.identifier.scopus2-s2.0-2442696379en_US
dc.identifier.isiWOS:000221869800014en_US
dc.relation.volume18en_US
dc.relation.issue2en_US
dc.description.firstpage251en_US
dc.description.lastpage256en_US
dc.description.thirdmissionNot applicableen_US
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeArticle-
item.fulltextNo Fulltext-
crisitem.author.orcid9810-
crisitem.author.orcid0000-0003-4187-3919-
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