Please use this identifier to cite or link to this item:
|Title:||Antioxidant activity of galloyl quinic derivatives isolated from P. lentiscus leaves||Authors:||Baratto, Maria Camilla
|Keywords:||EPR, Hydroxyl and superoxide radicals, LDL, Spin trapping||Issue Date:||2003||Project:||None||Journal:||FREE RADICAL RESEARCH||Abstract:||
The antioxidant properties of galloyl quinic derivatives isolated from Pistacia lentiscus L. leaves have been investigated by means of Electron Paramagnetic Resonance spectroscopy (EPR) and UV-Vis spectrophotometry. Antioxidant properties have been also estimated using the biologically relevant LDL test. The scavenger activities of gallic acid, 5-O-galloyl, 3,5-O-digalloyl, 3,4,5-O-trigalloyl quinic acid derivatives, have been estimated against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, superoxide (O2-) radical, and hydroxyl (OH) radical. On the whole, the scavenger activity raised as the number of galloyl groups on the quinic acid skeleton increased. The half-inhibition concentrations (IC50) of di- and tri-galloyl derivatives did not exceed 30 mM for all the tested free radicals. All the tested metabolites strongly reduced the oxidation of low-density lipoproteins (LDL), following a trend similar to that observed for the scavenger ability against OH radical.
|Appears in Collections:||Publications|
Show full item record
checked on May 5, 2021
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.