Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/4809
Title: Antioxidant activity of galloyl quinic derivatives isolated from P. lentiscus leaves
Authors: Baratto, Maria Camilla 
Tattini, M.
Galardi, C.
Pinelli, P.
Romani, A.
Visioli, F.
Basosi, Riccardo 
Pogni, Rebecca 
Keywords: EPR, Hydroxyl and superoxide radicals, LDL, Spin trapping
Issue Date: 2003
Project: None 
Journal: FREE RADICAL RESEARCH
Abstract: 
The antioxidant properties of galloyl quinic derivatives isolated from Pistacia lentiscus L. leaves have been investigated by means of Electron Paramagnetic Resonance spectroscopy (EPR) and UV-Vis spectrophotometry. Antioxidant properties have been also estimated using the biologically relevant LDL test. The scavenger activities of gallic acid, 5-O-galloyl, 3,5-O-digalloyl, 3,4,5-O-trigalloyl quinic acid derivatives, have been estimated against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, superoxide (O2-) radical, and hydroxyl (OH) radical. On the whole, the scavenger activity raised as the number of galloyl groups on the quinic acid skeleton increased. The half-inhibition concentrations (IC50) of di- and tri-galloyl derivatives did not exceed 30 mM for all the tested free radicals. All the tested metabolites strongly reduced the oxidation of low-density lipoproteins (LDL), following a trend similar to that observed for the scavenger ability against OH radical.
Description: 
36714
URI: http://hdl.handle.net/20.500.12779/4809
ISSN: 1071-5762
DOI: 10.1080/1071576031000068618
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