Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/4419
Title: Synthesis and biological evaluation of 2-methoxy- and 2-Methylthio-6-[(2′-alkylamino)ethyl]-4(3H)-pyrimidinones with anti-rubella virus activity
Authors: Botta, Maurizio 
Occhionero, Francesca
Nicoletti, Rosario
Mastromarino, Paola
Conti, Cinzia
Magrini, Maurizio
Saladino, Raffaele
Issue Date: 1999
Project: None 
Journal: BIOORGANIC & MEDICINAL CHEMISTRY
Abstract: 
The synthesis of a new family of antiviral compounds, 2-methoxy-, and 2-methylthio-6-[(2'-alkylamino)ethyl]-4(3H)-pyrimidinones, has been accomplished. The activity of these agents against positive strand (rubella virus and sindbis virus) and negative strand (vesicular stomatitis virus) RNA viruses is reported. Some of these compounds are efficient and selective inhibitors of rubella virus.
Description: 
22381
URI: http://hdl.handle.net/20.500.12779/4419
ISSN: 0968-0896
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