Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/4321
Title: Small ring constrained peptidomimetics. Synthesis of aziridine parallel beta-sheet mimetics
Authors: S. N., Filigheddu
Taddei, Maurizio 
Issue Date: 1998
Project: None 
Journal: TETRAHEDRON LETTERS
Abstract: 
The synthesis of a series of novel amino acids and peptides containing an aziridine ring is described. Their preparation is based on the Gabriel-Cromwell reaction of amino acids or peptides with different 2-bromo acrylates and acrylamides. These products are constituted by a turned scaffold (the aziridine) where two parallel peptidic strands can be grown to produce a beta-sheet mimetic. (C) 1998 Elsevier Science Ltd. All rights reserved.
Description: 
45971
URI: http://hdl.handle.net/20.500.12779/4321
ISSN: 0040-4039
DOI: 10.1016/S0040-4039(98)00632-7
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