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|Title:||Synthesis of amphiphilic polyhydroxylated pyrrolidines as potential glycosidase inhibitors||Authors:||A., Esposito
|Issue Date:||1998||Project:||None||Journal:||TETRAHEDRON LETTERS||Abstract:||
Several polyhydroxylated pyrrolidines with an aliphatic long chain on the ring nitrogen were prepared starting from D-mannitol. An amphiphilic bis-azasugar scaffold has been also prepared. These products behave as cationic surfactants and show a promising anti HIV-I activity. (C) 1998 Elsevier Science Ltd. All rights reserved.
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