Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/4232
Title: Stereoconvergent synthesis of (2S,3S,8S,9S,4E,6E)-N-Boc-ADDA starting from (S)-serine and (S)-phenyllactic acid
Authors: F., Daniello
A., Mann
A., Schoenfelder
Taddei, Maurizio 
Issue Date: 1997
Project: None 
Journal: TETRAHEDRON
Abstract: 
The important naturally occurring beta-amino acid N-Boc-ADDA is prepared following a disconnection of the C-C bond between the two E,E double bonds. The stereochemistry of the two synthons was controlled using the alkylation of chiral bromoalienes derived from naturally occurring (S)-serine and (S)-phenyllactic acid. The cupration of bromoallenes derived from (S)-serine also provides a general method for the synthesis of chiral beta-alkylated aspartic acid derivatives. (C) 1997, Elsevier Science Ltd.
Description: 
45966
URI: http://hdl.handle.net/20.500.12779/4232
ISSN: 0040-4020
DOI: 10.1016/S0040-4020(96)01056-3
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