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|Title:||Chelating agents as potential antitumorals. 2-quinolylhydrazones and bis-2-quinolylhydrazones. I||Authors:||Savini, Luisa
|Keywords:||2-quinolylhydrazone,bis-2-quinolylhydrazone,pyruvic carboxaldehyde,chelating agent,cytotoxicity||Issue Date:||1995||Project:||None||Journal:||EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY||Abstract:||
A number of pyruvic acid, methylpyruvate and pyruvic carboxaldehyde 2-quinolylhydrazones have been synthesized. Some bis-2-quinolylhydrazones were also obtained during the reaction with pyruvic carboxaldehyde. All these compounds have been evaluated for cytotoxicity and most display a significant in vitro activity against a variety of cell lines.
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