Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/4038
Title: The sequence organization of the long arm pseudoautosomal region of the human sex chromosomes.
Authors: K., Kvaloy
Galvagni, Federico 
W., Brown
Issue Date: 1994
Project: None 
Journal: HUMAN MOLECULAR GENETICS
Abstract: 
We have analysed the sequence organization of the pseudoautosomal region at the telomeres of the long arms of the human sex chromosomes and shown that it is 320 kb long. A LINE sequence is present on both the X and Y chromosomes immediately adjacent to the breakpoint in homology suggesting that the homology arose as a result of an ectopic recombination event mediated by LINE sequences originally present in non-homologous stretches of X and Y chromosomal DNA. This led to the translocation of sequences from the X chromosome telomere onto the Y chromosome and created a new pseudoautosomal region.
Description: 
25601
URI: http://hdl.handle.net/20.500.12779/4038
ISSN: 0964-6906
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