Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/4025
Title: New Heterocyclic Analogs of Suramin with bFGF Inhibiting Activity. Synthesis, SAR and Possible Mode of Action
Authors: G., Biasoli
Botta, Maurizio 
M., Ciomei
Corelli, Federico 
M., Grandi
Manetti, Fabrizio 
N., Mongelli
A., Paio
Issue Date: 1994
Project: None 
Journal: MEDICINAL CHEMISTRY RESEARCH
Abstract: 
Some heterocyclic analogs of suramin with potent and selective basic fibroblast growth factor (bFGF) complexing activity have been synthesized. The possible mode of action of these compounds, deduced on the basis of SAR, biological properties and molecular modeling studies, entails a unique bidentate binding of the ligands to both the heparin and receptor binding sites of the growth factor
Description: 
25418
URI: http://hdl.handle.net/20.500.12779/4025
ISSN: 1054-2523
DOI: 10.1016/S0968-0896(98)00052-2
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