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|Title:||Approaches To the Synthesis of 2-sila-1-carba-cephalosporins||Authors:||S., Gehanne
|Issue Date:||1994||Project:||None||Journal:||TETRAHEDRON LETTERS||Abstract:||
A condensed beta-lactam containing a silicon atom in the B ring was prepared starting from allyldimethyl-(chloromethyl)-silane. The simple 6-unsubstituted structure did not show any relevant antibiotic activity, but it represents the first example of the synthesis of a molecule with a structure of a ''sila-cephem''.
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