Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/3975
Title: Studies on the biological effects of ozone: 4. Cytokine productionand glutathione levels in human erythrocytes.
Authors: Bocci, V
Luzzi, E
Corradeschi, F
Ricci, L
Rossi, R
Cardaioli, E
Di Simplicio, P
Issue Date: 1993
Project: None 
Journal: JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS
Abstract: 
We have investigated the effect of various concentrations of ozone on human blood aiming to correlate the production of cytokines with depletion of reduced glutathione and hemolysis. As erythrocytes constitute the bulk of blood cells and represent the main target of ozone they have been taken as a useful marker of its oxidative activity. It appears that a transient exposure (30 sec) of blood of up to 78 micrograms ozone per ml of blood does not depress the production of cytokines even though there is a slight increase of hemolysis and a small decrease of intracellular reduced glutathione. In contrast either a constant (up to 30 sec) exposure to an ozone flux or a high ozone concentration (108 micrograms/ml) markedly decreases reduced glutathione levels and depresses cytokine production.
Description: 
44445
URI: http://hdl.handle.net/20.500.12779/3975
ISSN: 0393-974X
Appears in Collections:Publications

Show full item record

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.