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|Title:||Pyrazolo[4,3-c]quinolines. Synthesis and specific inhibition of benzodiazepine receptor binding (Note I)||Authors:||Savini, Luisa
Romeo, M. R.
|Issue Date:||1993||Project:||None||Journal:||IL FARMACO||Abstract:||
A series of 2-arylpyrazolo[4,3-c] quinolin-3-one derivatives, bearing different substituents in the two aromatic rings, were prepared and tested for their ability to displace [H-3] flunitrazepam from rat brain membranes. Some compounds have shown an affinity for receptors comparable and sometimes higher than that of CGS series.
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