Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/3905
Title: CONFORMATIONAL EFFECTS ON THE STEREOCHEMICAL COURSE OF THE NABH4 REDUCTION OF SUBSTITUTED BICYCLO[3.3.1]NONAN-2-ONES
Authors: Gambacorta, A
Dellojacono, Ar
Botta, Maurizio 
Tafi, Andrea 
Issue Date: 1992
Project: None 
Journal: GAZZETTA CHIMICA ITALIANA
Abstract: 
Molecular mechanics calculations for the 1-substituted bicyclo[3.3.1]nonan-2-ones 2a-d show that the amount of the chair-boat conformation increases as the size of the substituent at C1 increases. This result sharply fits with the stereochemical course of NaBH4 reductions of ketones 2a-d if axial attack on the chair-boat conformation and equatorial attack on the chair-chair one are assumed to be preferential.
Description: 
49330
URI: http://hdl.handle.net/20.500.12779/3905
ISSN: 0016-5603
Appears in Collections:Publications

Show full item record

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.