Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/3900
Title: Synthesis of two novel heparinizable polymeric materials starting from an ethylene/vinyl alcohol/vinyl acetate terpolymer
Authors: R., Barbucci
Benvenuti, Manuela 
Magnani, Agnese 
F., Tempesti
Issue Date: 1992
Project: None 
Journal: DIE MAKROMOLEKULARE CHEMIE
Abstract: 
A partially hydrolyzed ethylene/vinyl acetate (EVA) copolymer was modified through the covalent binding of a heparin-complexing polymer, in order to improve its blood compatibility. Two different heparinizable polymeric materials (EVAPA I and II) were obtained by a two-step reaction between an ethylene/vinyl alcohol/vinyl acetate (EVALVA) terpolymer and a poly-(amido-amine) (N2LL) using either hexamethylene diisocyanate (HMDI) or 1,1'-carbonyldimidazole (CDI) as bifunctional agents. EVALVA terpolymer was prepared by a homogeneous saponification process, and the percentage of hydrolysis was determined by an analytical method. EVAPA I and II syntheses were followed by FT-IR/ATR (Fourier Transform Infrared/Attenuated Total Reflection) spectroscopy.
Description: 
55669
URI: http://hdl.handle.net/20.500.12779/3900
ISSN: 0025-116X
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