Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12779/3735
Title: Conformation and dynamics of ranitidine in solution as detected by 1H and 13C NMR spectroscopy
Authors: Gaggelli, Elena 
Marchettini, Nadia
Sega, Alessandro 
Valensin, Gianni 
Issue Date: 1988
Project: None 
Journal: MAGNETIC RESONANCE IN CHEMISTRY
Abstract: 
Conformational and dynamic features of ranitidine were delineated by 1H and 13C NMR 1D and 2D spectroscopy. Spin–lattice relaxation rates and homo- and hetero-nuclear NOEs were measured. An extended conformation was shown to predominate in solution, with restricted segmental motion. The main reorientational motion and some of the internal motions were characterized in terms of stochastic internal motion around a molecular axis that reorients isotropically. Selective irradiation methods were used to obtain relevant conformational parameters.
Description: 
50089
URI: http://hdl.handle.net/20.500.12779/3735
ISSN: 0749-1581
DOI: 10.1002/mrc.1260261202
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