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|Title:||Molecular analysis of a case of IgA2 deficiency.||Authors:||Oliviero, Salvatore
van Loghem, E
de Lange, G
|Issue Date:||1986||Project:||None||Journal:||JOURNAL OF IMMUNOGENETICS||Abstract:||
A family with two members with selective IgA2 deficiency was analysed by direct gene analysis with different probes for the IgCH region. No gross gene deletions or rearrangements were detected. Genetic analysis based on serological and molecular markers did not rule out linkage with the IgCH region. However, a defect of other genes not linked to the Ig heavy chain region and controlling the expression of IgA may be possible as well.
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