Browsing by Author U., Hubscher

Showing results 1 to 3 of 3
Issue DateTitleAuthor(s)Third Mission
2004Effects of Drug Resistance Mutations L100I and V106A on the Binding of Pyrrolobenzoxazepinone Nonnucleoside Inhibitors to the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Catalytic ComplexG. A., Locatelli; Campiani, Giuseppe ; R., Cancio; E., Morelli; A., Ramunno; Gemma, Sandra ; U., Hubscher; S., Spadari; G., MagaNot applicable
2008Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the ‘‘primer grip’’ region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants.S., Zanoli; Gemma, Sandra ; Butini, Stefania ; Brindisi, Margherita ; B. P., Joshi; Campiani, Giuseppe ; C., Fattorusso; M., Persico; E., Crespan; R., Cancio; S., Spadari; U., Hubscher; G., MagaNot applicable
2001The Stereoselective Targeting of a Specific Enzyme-Substrate Complex is the Molecular Mechanism for the Synergic Inhibition of HIV-1 Reverse Transcriptase by (R)-(-)PPO464, a Novel Generation of Non-Nucleoside InhibitorsG., Maga; A., Ramunno; Nacci, Vito; G., Locatelli; S., Spadari; F., Baldanti; S., Paolucci; M., Zavattoni; A., Bergamini; B., Galletti; S., Muck; U., Hubscher; Giorgi, Gianluca ; G., Guiso; S., Caccia; Campiani, Giuseppe Not applicable