Browsing by Author Pasquini, Serena


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Issue DateTitleAuthor(s)Third Mission
20111-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB1 and CB2 receptor ligandsPiscitelli, F; Ligresti, A; LA REGINA, G; Gatti, V; Brizzi, Antonella ; Pasquini, Serena; Allarà, M; CARAI M. A., M; Novellino, E; Colombo, G; DI MARZO, V; Corelli, Federico ; Silvestri, R.Not applicable
2009The 4-Quinolone-3-carboxylic Acid Motif as a Multivalent Scaffold in Medicinal ChemistryMugnaini, Claudia ; Pasquini, Serena; Corelli, Federico Not applicable
2011Activation of the GABAB receptor prevents nicotine-induced locomotor stimulation in miceLobina, C.; Carai, M. A. M.; Froestl, W.; Mugnaini, Claudia ; Pasquini, Serena; Corelli, Federico ; G. e. s. s. a. G., L.; Colombo, G.Not applicable
2012The bioisosteric concept applied to cannabinoid ligandsMugnaini, Claudia ; Pasquini, Serena; Corelli, Federico Not applicable
2012Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptorCastelli, M. P.; Casu, A.; Casti, P.; Lobina, C.; Carai, M. A. M.; Colombo, G.; Solinas, M.; Giunta, D.; Mugnaini, Claudia ; Pasquini, Serena; Tafi, Andrea ; Brogi, Simone; Gessa, G. L.; Corelli, Federico Not applicable
2012Comparison of the effect of the positive allosteric modulator of the GABAb receptor, GS39783, on alcohol self-administration in three different lines of alcohol-preferring ratsMaccioni, P.; Zaru, A.; Loi, B.; Lobina, C.; Carai, M. A. M.; Gessa, G. L.; Capra, A.; Mugnaini, Claudia ; Pasquini, Serena; Corelli, Federico ; Hyytiä, P.; Lumeng, L.; Colombo, G.Not applicable
2012Design, Synthesis, and Pharmacological Characterization of Indole-3-ylacetamides, Indole-3-yloxoacetamides, and Indole-3-ylcarboxamides: Potent and Selective CB2 Cannabinoid Receptor Inverse AgonistsPasquini, Serena; Mugnaini, Claudia ; Ligresti, A.; Tafi, Andrea ; Brogi, Simone; Falciani, C.; Pedani, Valentina; Pesco, N.; Guida, F.; Luongo, L.; Varani, K.; Borea, P. A.; Maione, S.; Di Marzo, V.; Corelli, Federico Not applicable
2010In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB2 receptor inverse agonistsM. G., Cascio; D., Bolognini; R. G., Pertwee; E., Palazzo; Corelli, Federico ; Pasquini, Serena; V., DI MARZO; S., MaioneNot applicable
2011Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 4. Identification of New Potent and Selective Ligands for the Cannabinoid Type 2 Receptor with Diverse Substitution Patterns and Antihyperalgesic Effects in Mice.Pasquini, Serena; DE ROSA, Maria; Pedani, Valentina; Mugnaini, Claudia ; Guida, F; Luongo, L; DE CHIARO, M; Maione, S; Dragoni, Stefania; Frosini, Maria; Ligresti, A; DI MARZO, V; Corelli, Federico Not applicable
2012Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach.Mugnaini, Claudia ; Nocerino, S.; Pedani, Valentina; Pasquini, Serena; Tafi, Andrea ; De Chiaro, M.; Bellucci, L.; Valoti, Massimo; Guida, F.; Luongo, L.; Dragoni, Stefania; Ligresti, A.; Rosenberg, A.; Bolognini, D.; Cascio, M. G.; Pertwee, R. G.; Moaddel, R.; Maione, S.; Di Marzo, V.; Corelli, Federico Not applicable
2008Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 1. Synthesis and Structure-Activity Relationship of a Class of Human Immunodeficiency Virus type 1 Integrase Inhibitors.Pasquini, Serena; Mugnaini, Claudia ; Tintori, Cristina; Botta, Maurizio ; A., Trejos; R. K., Arvela; M., Larhed; M., Vitvrouw; M., Michiels; F., Christ; Z., Debyser; Corelli, Federico Not applicable
2008Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 2. Synthesis and Structure-Activity Relationship of Potent and Selective Cannabinoid-2 Receptor Agonists Endowed with Analgesic Activity in Vivo.Pasquini, Serena; Botta, Lorenzo; Semeraro, Teresa; Mugnaini, Claudia ; Ligresti, A; Palazzo, E; Maione, S; DI MARZO, V; Corelli, Federico Not applicable
2010Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 3. Synthesis, Structure-Affinity Relationships, and Pharmacological Characterization of 6-Substituted 4-Quinolone-3-carboxamides as Highly Selective Cannabinoid-2 Receptor LigandsPasquini, Serena; Ligresti, A; Mugnaini, Claudia ; Semeraro, Teresa; Cicione, L; DE ROSA, Maria; Guida, F; Luongo, L; DE CHIARO, M; CASCIO M., G; Bolognini, D; Marini, P; Pertwee, R; Maione, S; DI MARZO, V; Corelli, Federico Not applicable
2012Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 6. Synthesis and Pharmacological Evaluation of 7-Substituted 4-Quinolone-3-carboxamide Derivatives as High Affinity Ligands for Cannabinoid ReceptorsPasquini, Serena; DE ROSA, Maria; Ligresti, A.; Mugnaini, Claudia ; Brizzi, Antonella ; Caradonna, N. P.; Cascio, M. G.; Bolognini, D.; Pertwee, R. G.; Di Marzo, V.; Corelli, Federico Not applicable
2004Microwave-assisted synthesis and biological evaluation of novel uracil derivatives inhibiting human thymidine phosphorylaseCorelli, Federico ; Botta, Maurizio ; Lossani, Andrea; Pasquini, Serena; Spadari, Silvio; Focher, FedericoNot applicable
2012A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injuryContartese, Antonella; Valoti, Massimo; Corelli, Federico ; Pasquini, Serena; Mugnaini, Claudia ; Pessina, Federica; Aldinucci, Carlo; Sgaragli, GIAN PIETRO; Frosini, MariaNot applicable
2009Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N-alkylacetamides as CB2 receptor ligandsPasquini, Serena; Mugnaini, Claudia ; Brizzi, Antonella ; A., Ligresti; V., DI MARZO; C., Ghiron; Corelli, Federico Not applicable
2010Reduction by the positive allosteric modulator of the GABAB receptor, GS39783, of alcohol self-administration in Sardinian alcohol-preferring rats exposed to the “sipper” procedureMaccioni, P; Flore, P; CARAI M. A., M; Mugnaini, Claudia ; Pasquini, Serena; Corelli, Federico ; GESSA G., L; Colombo, G.Not applicable
2011Regioselective functionalization of quinolin-4(1H)-ones via sequential palladium-catalyzed reactionsMugnaini, Claudia ; Falciani, Chiara; DE ROSA, Maria; Brizzi, Antonella ; Pasquini, Serena; Corelli, Federico Not applicable
2010Synthesis and biological evaluation of New N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligandsRomano, Silvestri; Alessia, Ligresti; GIUSEPPE LA, Regina; Francesco, Piscitelli; Valerio, Gatti; Antonio, Lavecchia; Pasquini, Serena; Marco, Allarà; Noemi, Fantini; MAURO ANTONIO MARIA, Carai; Chiara, Bigogno; MARCO GIULIO, Rozio; Roberta, Sinisi; Ettore, Novellino; Giancarlo, Colombo; VINCENZO DI, Marzo; Giulio, Dondio; Brizzi, Antonella ; Corelli, Federico Not applicable