Browsing by Author Novellino, Ettore

Showing results 1 to 17 of 17
Issue DateTitleAuthor(s)Third Mission
2017Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluationBrogi, Simone; Maramai, Samuele ; Brindisi, Margherita ; Chemi, Giulia ; Porcari, Valentina; Corallo, Claudio; Gennari, Luigi; Novellino, Ettore; Ramunno, Anna; Butini, Stefania ; Campiani, Giuseppe ; Gemma, Sandra Not applicable
2017Benzodiazepine scaffold as drug-like molecular simplification of FR235222: A chemical tool for exploring HDAC inhibitionRANDINO, ROSARIO; Moronese, Ilaria; Cini, Elena ; Bizzarro, Valentina; Persico, Marco; Grimaldi, Manuela; Scrima, Mario; D’Ursi, Anna Maria; Novellino, Ettore; Sobarzo Sánchez, Eduardo; Rastrelli, Luca; Fattorusso, Caterina; Petrella, Antonello; RODRIQUEZ, MANUELA; Taddei, Maurizio Not applicable
2016Development of novel cyclic peptides as pro-apoptotic agentsBrindisi, Margherita ; Maramai, Samuele ; Brogi, Simone; Fanigliulo, Emanuela; Butini, Stefania ; Guarino, Egeria; Casagni, Alice; Lamponi, Stefania ; Bonechi, Claudia ; Nathwani, Seema M; Finetti, Federica ; Ragonese, Francesco; Arcidiacono, Paola; Campiglia, Pietro; Valenti, Salvatore; Novellino, Ettore; Spaccapelo, Roberta; Morbidelli, Lucia; Zisterer, Daniela M; Williams, Clive D; Donati, Alessandro ; Baldari, Cosima; Campiani, Giuseppe ; Ulivieri, Cristina; Gemma, Sandra Not applicable
2015Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agentsBrogi, Simone; Brindisi, Margherita ; Joshi, Bhupendra P.; Sanna Coccone, Salvatore; Parapini, Silvia; Basilico, Nicoletta; Novellino, Ettore; Campiani, Giuseppe ; Gemma, Sandra ; Butini, Stefania Not applicable
2016Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibitionBrindisi, Margherita ; Brogi, Simone; Maramai, Samuele ; Grillo, Alessandro; Borrelli, Giuseppe; Butini, Stefania ; Novellino, Ettore; Allarà, Marco; Ligresti, Alessia; Campiani, Giuseppe ; Di Marzo, Vincenzo; Gemma, Sandra Not applicable
2016In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitorsBrogi, Simone; Giovani, Simone; Brindisi, Margherita ; Gemma, Sandra ; Novellino, Ettore; Campiani, Giuseppe ; Blackman, Michael J; Butini, Stefania Not applicable
2018A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agentsFederico, Stefano ; Khan, Tuhina ; Relitti, Nicola ; Chemi, Giulia ; Brindisi, Margherita ; Brogi, Simone; Novellino, Ettore; Zisterer, Daniela M.; Campiani, Giuseppe ; Gemma, Sandra ; Butini, Stefania Not applicable
2018Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studiesBrindisi, Margherita ; Senger, Johanna; Cavella, Caterina; Grillo, Alessandro; Chemi, Giulia ; Gemma, Sandra ; Cucinella, Dora Mariagrazia; Lamponi, Stefania ; Sarno, Federica; Iside, Concetta; Nebbioso, Angela; Novellino, Ettore; Shaik, Tajith Baba; Romier, Christophe; Herp, Daniel; Jung, Manfred; Butini, Stefania ; Campiani, Giuseppe ; Altucci, Lucia; Brogi, SimoneNot applicable
2016Phenylpyrrole-based HDAC inhibitors: synthesis, molecular modeling and biological studiesBrindisi, Margherita ; Cavella, Caterina; Brogi, Simone; Nebbioso, Angela; Senger, Johanna; Maramai, Samuele ; Ciotta, Alfonso; Iside, Concetta; Butini, Stefania ; Lamponi, Stefania ; Novellino, Ettore; Altucci, Lucia; Jung, Manfred; Campiani, Giuseppe ; Gemma, Sandra Not applicable
2015Plasmodium falciparum subtilisin-like protease 1: discovery of potent difluorostatone-based inhibitorsGiovani, Simone; Penzo, Maria; Butini, Stefania ; Brindisi, Margherita ; Gemma, Sandra ; Novellino, Ettore; Campiani, Giuseppe ; Blackman, Michael J.; Brogi, SimoneNot applicable
2018(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigationBrogi, Simone; Brindisi, Margherita ; Butini, Stefania ; Kshirsagar, Giridhar U.; Maramai, Samuele ; Chemi, Giulia ; Gemma, Sandra ; Campiani, Giuseppe ; Novellino, Ettore; Fiorenzani, Paolo; Pinassi, Jessica; Aloisi, Anna Maria; Gynther, Mikko; Venskutonytė, Raminta; Han, Liwei; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S.Not applicable
2016Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside InhibitorsSavi, Lida; Brindisi, Margherita ; Alfano, Gloria; Butini, Stefania ; La Pietra, Valeria; Novellino, Ettore; Marinelli, Luciana; Lossani, Andrea; Focher, Federico; Cavella, Caterina; Campiani, Giuseppe ; Gemma, Sandra Not applicable
2019Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agentsBrindisi, Margherita ; Ulivieri, Cristina; Alfano, Gloria; Gemma, Sandra ; de Asís Balaguer, Francisco; Khan, Tuhina ; Grillo, Alessandro; Chemi, Giulia ; Menchon, Grégory; Prota, Andrea E; Olieric, Natacha; Lucena-Agell, Daniel; Barasoain, Isabel; Diaz, J Fernando; Nebbioso, Angela; Conte, Mariarosaria; Lopresti, Ludovica ; Magnano, Stefania; Amet, Rebecca; Kinsella, Paula; Zisterer, Daniela M; Ibrahim, Ola; O'Sullivan, Jeff; Morbidelli, Lucia; Spaccapelo, Roberta; Baldari, Cosima; Butini, Stefania ; Novellino, Ettore; Campiani, Giuseppe ; Altucci, Lucia; Steinmetz, Michel O; Brogi, SimoneNot applicable
2015Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput dockingBrindisi, Margherita ; BROGI, SIMONE; Relitti, Nicola ; VALLONE, ALESSANDRA; Butini, Stefania ; Gemma, Sandra ; Novellino, Ettore; Colotti, Gianni; Angiulli, Gabriella; Di Chiaro, Francesco; Fiorillo, Annarita; Ilari, Andrea; Campiani, Giuseppe Not applicable
2015Synthetic spirocyclic endoperoxides: new antimalarial scaffoldsBrindisi, Margherita ; Gemma, Sandra ; Kunjir, Sanil; Di Cerbo, Luisa; Brogi, Simone; Parapini, Silvia; D'Alessandro, Sarah; Taramelli, Donatella; Habluetzel, Annette; Tapanelli, Sofia; Lamponi, Stefania ; Novellino, Ettore; Campiani, Giuseppe ; Butini, Stefania Not applicable
2018Synthetic studies toward bicyclic endoperoxides presenting polar side chainsGemma, Sandra ; di Cerbo, Luisa; Relitti, Nicola ; Vallone, Alessandra; Brindisi, Margherita ; Brogi, Simone; Chemi, Giulia ; Novellino, Ettore; Campiani, Giuseppe ; Butini, Stefania Not applicable
2016Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitorsBrindisi, Margherita ; Brogi, Simone; Giovani, Simone; Gemma, Sandra ; Lamponi, Stefania ; DE LUCA, Filomena; Novellino, Ettore; Campiani, Giuseppe ; Docquier, JEAN DENIS; Butini, Stefania Not applicable